BDBM50563345 CHEMBL4755735

SMILES COc1ccc(cc1)S(=O)(=O)N1C[C@@H](C[C@@H]1C(=O)NO)NC(=O)C(C)(C)C

InChI Key InChIKey=UIEWQARSDPRMDM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50563345   

Target72 kDa type IV collagenase(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50563345(CHEMBL4755735)
Affinity DataKi:  26nMAssay Description:Inhibition of MMP2 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 5 min followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50563345(CHEMBL4755735)
Affinity DataKi:  123nMAssay Description:Inhibition of MMP9 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 5 min followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50563345(CHEMBL4755735)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human CA1 incubated for 15 mins by stopped-flow CO2 hydration kinetic assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50563345(CHEMBL4755735)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human CA2 incubated for 15 mins by stopped-flow CO2 hydration kinetic assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed