BDBM50563378 CHEMBL4790766

SMILES CCOC(=O)c1c(C)nc(nc1-c1ccc(OC)c(OC)c1)N1CCN(CC1)S(=O)(=O)c1ccc(NC(C)=O)c(Cl)c1

InChI Key InChIKey=IBSHITWLGHMGMC-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50563378   

TargetAcetylcholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50563378(CHEMBL4790766)
Affinity DataKi:  8nMAssay Description:Non-competitive inhibition of AChE in human erythrocytes measured at 2 mins interval for 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50563378(CHEMBL4790766)
Affinity DataIC50: 47nMAssay Description:Inhibition of AChE in human erythrocytes using acetylthiocholineiodide as substrate pre-incubated for 10 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50563378(CHEMBL4790766)
Affinity DataIC50: 159nMAssay Description:Inhibition of BuChE in human serum using butyrylthiocholineiodide as substrate pre-incubated for 10 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed