BDBM50563429 CHEMBL4794140

SMILES Oc1cc(ccc1F)-c1nc([nH]c1-c1ccnc(NCCCNS(=O)(=O)c2cccc(F)c2)n1)-c1ccccc1

InChI Key InChIKey=BPMADPQKXXYMGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563429   

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563429(CHEMBL4794140)
Affinity DataIC50: 30nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563429(CHEMBL4794140)
Affinity DataIC50: 140nMAssay Description:Inhibition of p38 alpha (unknown origin) using Ser/Thr 15 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed