BDBM50563433 CHEMBL4756408

SMILES Oc1cc(ccc1Cl)-c1nc([nH]c1-c1ccnc(NCCCNS(=O)(=O)c2ccc(Br)cc2)n1)-c1ccccc1

InChI Key InChIKey=QOXYYZBIJGCIBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50563433   

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50563433(CHEMBL4756408)
Affinity DataIC50: 22nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using Ser/Thr 03 as substrate after 1 hr in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed