BDBM50563963 CHEMBL4782221

SMILES Cc1noc2c(Br)cc(cc12)-c1nc2ccc(cc2n1CC1CCCCC1)N1CCOCC1

InChI Key InChIKey=DWOKCNGITTUDTF-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563963   

TargetBromodomain-containing protein 4(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50563963(CHEMBL4782221)
Affinity DataKd:  159nMAssay Description:Binding affinity to human recombinant His6-tagged BRD4 bromodomain 1 (N44 to E168 residues) expressed in Escherichia coli BL21 (DE3) cells assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50563963(CHEMBL4782221)
Affinity DataIC50: 300nMAssay Description:Inhibition of HYSGRGK(Ac)GGK(Ac)GLGK(Ac)GGAK(Ac)RHRK(Biotin)-OH binding to recombinant human His6-tagged BRD4 bromodomain 1 (N44 to E168 residues) ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed