BDBM50563977 CHEMBL4797518

SMILES CCOC(=O)c1ccc(NC(=S)N\N=C\c2cc(OC)c(OC)c(Br)c2Br)cc1

InChI Key InChIKey=BWWCPTJDCGETQL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563977   

TargetPoly [ADP-ribose] polymerase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50563977(CHEMBL4797518)
Affinity DataIC50: 5.83E+4nMAssay Description:Inhibition of human recombinant GST-tagged PARP-1 expressed in Escherichia coli assessed as reduction in NAD+-dependent ADP ribosylation incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50563977(CHEMBL4797518)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged PARP-2 expressed in Baculovirus infected Sf9 cells assessed as reduction in NAD+-dependent ADP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed