BDBM50564240 CHEMBL4786169

SMILES NC(COCc1cn(CCOCCOc2ccc(cc2)-c2cn(C[C@@H]3NC[C@@H](O)[C@H]3O)nn2)nn1)(COCc1cn(CCOCCOc2ccc(cc2)-c2cn(C[C@@H]3NC[C@@H](O)[C@H]3O)nn2)nn1)COCc1cn(CCOCCOc2ccc(cc2)-c2cn(C[C@@H]3NC[C@@H](O)[C@H]3O)nn2)nn1

InChI Key InChIKey=RFKARSAQDWOGOR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50564240   

TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564240(CHEMBL4786169)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50564240(CHEMBL4786169)
Affinity DataKi:  5.50E+4nMAssay Description:Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed