BDBM50564474 CHEMBL4795802

SMILES Cc1ccc(Nc2nc(Cl)nc3n(Cc4ccc(cc4)C(=O)Nc4ccccc4N)cnc23)cc1

InChI Key InChIKey=XHELPOUKGPDRRH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50564474   

TargetHistone deacetylase 2(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50564474(CHEMBL4795802)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human HDAC2 using FLUOR-DE-LYS-Green as substrate incubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50564474(CHEMBL4795802)
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human HDAC1 using SIRT1 as substrate incubated for 10 mins followed by substrate addition and measured after 30 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50564474(CHEMBL4795802)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CDK2/CyclinA2 expressed in baculovirus infected Sf21 cells using histone H1 as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed