BDBM50564718 CHEMBL4781618

SMILES CN1CCC(=CC1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(Sc2nc3ccccc3n2C)cc1

InChI Key InChIKey=JPLLQSBSTHWUIK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50564718   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50564718(CHEMBL4781618)
Affinity DataIC50: 14nMAssay Description:Inhibition of human CDK9/cyclin T in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50564718(CHEMBL4781618)
Affinity DataIC50: 160nMAssay Description:Inhibition of human GSK3beta in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
University Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50564718(CHEMBL4781618)
Affinity DataIC50: 284nMAssay Description:Inhibition of human CDK5/p25 in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50564718(CHEMBL4781618)
Affinity DataIC50: 349nMAssay Description:Inhibition of human CDK2/cyclin A in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed