BDBM50564895 CHEMBL4797998

SMILES COc1ccc2cc(oc2c1)C(=O)NCCN(C)C

InChI Key InChIKey=ORKBRHLZMASEDO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50564895   

TargetCytochrome P450 2D6(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50564895(CHEMBL4797998)
Affinity DataIC50: 7.84E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 5 mins followed by NADPH addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50564895(CHEMBL4797998)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate incubated for 5 mins followed by NADPH addition and measured after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50564895(CHEMBL4797998)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 5 mins followed by NADPH addition and measured after 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50564895(CHEMBL4797998)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate incubated for 5 mins followed by NADPH addition and measured after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50564895(CHEMBL4797998)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using omeprazole as substrate incubated for 5 mins followed by NADPH addition and measured after 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed