BDBM50565770 CHEMBL4782610

SMILES Fc1cccc(c1)-c1ccc(CN2CCS\C2=N\C#N)o1

InChI Key InChIKey=NPRYTDAPKPDRJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50565770   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50565770(CHEMBL4782610)
Affinity DataIC50: 5.97E+4nMAssay Description:Inhibition of human U-937 cells derived PDE4B using [3H] cAMP as substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50565770(CHEMBL4782610)
Affinity DataIC50: 8.95E+4nMAssay Description:Inhibition of PDE4B in human PBMC assessed as reduction in LPS-induced TNFalpha release preincubated for 30 mins followed by LPS stimulation and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed