BDBM50565786 CHEMBL4797637

SMILES Fc1cccc(F)c1-c1ccc(o1)C(=O)N1CCS\C1=N\C#N

InChI Key InChIKey=AKWZNMSEFZQWOY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50565786   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50565786(CHEMBL4797637)
Affinity DataIC50: 2.21E+4nMAssay Description:Inhibition of human U-937 cells derived PDE4B using [3H] cAMP as substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50565786(CHEMBL4797637)
Affinity DataIC50: 8.86E+4nMAssay Description:Inhibition of human U-937 cells derived PDE4D using [3H] cAMP as substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50565786(CHEMBL4797637)
Affinity DataIC50: 6.01E+4nMAssay Description:Inhibition of PDE4B in human PBMC assessed as reduction in LPS-induced TNFalpha release preincubated for 30 mins followed by LPS stimulation and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed