BDBM50565836 CHEMBL4795842

SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2cccc(c2)-c2cccc3ccccc23)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O

InChI Key InChIKey=VPORMYBONMHESW-UHFFFAOYSA-N

Data  4 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50565836   

TargetMelanocortin receptor 4(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50565836(CHEMBL4795842)
Affinity DataKi:  0.550nMAssay Description:Displacement of [125I]-[NIe,DPhe7]-alpha-MSH from human MC4R expressed in HEK293 cell membranes incubated for 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50565836(CHEMBL4795842)
Affinity DataKi:  0.551nMAssay Description:Displacement of [125I]-[NIe,DPhe7]-alpha-MSH from human MC4R expressed in HEK293 cell membranes incubated for 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50565836(CHEMBL4795842)
Affinity DataKi:  31.4nMAssay Description:Displacement of [125I]-[NIe,DPhe7]-alpha-MSH from human MC3R expressed in HEK293 cell membranes incubated for 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50565836(CHEMBL4795842)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells expressing the GScAMP22F cAMP reporter assessed as effect on cAMP accumulation by cAMP split...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50565836(CHEMBL4795842)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells expressing the GScAMP22F cAMP reporter assessed as effect on cAMP accumulation by cAMP split...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50565836(CHEMBL4795842)
Affinity DataKi:  32nMAssay Description:Displacement of [125I]-[NIe,DPhe7]-alpha-MSH from human MC3R expressed in HEK293 cell membranes incubated for 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50565836(CHEMBL4795842)
Affinity DataEC50:  153nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells expressing the GScAMP22F cAMP reporter assessed as effect on cAMP accumulation by cAMP split...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50565836(CHEMBL4795842)
Affinity DataEC50:  155nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells expressing the GScAMP22F cAMP reporter assessed as effect on cAMP accumulation by cAMP split...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed