BDBM50566143 CHEMBL4781051

SMILES CC(C)(CO)NC(=O)c1cc(n(n1)-c1ccc(cn1)C(F)(F)F)C(C)(C)C

InChI Key InChIKey=IIANDZHTDXIIKC-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50566143   

TargetCannabinoid receptor 2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50566143(CHEMBL4781051)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human CB2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production incubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50566143(CHEMBL4781051)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human CB2 receptor expressing CHO cells co-expressing Galpha16 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50566143(CHEMBL4781051)
Affinity DataEC50:  562nMAssay Description:Agonist activity at human CB2 receptor expressed in HEK293 cells after 24 hrs by luciferase reporter gene assay based Tango beta-arrestin recruitment...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50566143(CHEMBL4781051)
Affinity DataEC50:  1.84E+3nMAssay Description:Agonist activity at human CB1 receptor expressing CHO cells co-expressing Galpha16 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50566143(CHEMBL4781051)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293 cells after 24 hrs by luciferase reporter gene assay based Tango beta-arrestin recruitment...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed