BDBM50567218 CHEMBL4877968

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1S(C)(=O)=O)c1ccc(OCCN2CC(CF)C2)cc1F

InChI Key InChIKey=DLVPQVIQBVJNHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50567218   

TargetEstrogen receptor(Human)
Genentech

US Patent
LigandPNGBDBM50567218(CHEMBL4877968 | US20250114338, Example 232)
Affinity DataEC50:  0.192nMAssay Description:All of the exemplary Formula I compounds in Tables 1 and 2 were tested for binding to ERa (Estrogen Receptor alpha) and biological activity according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetEstrogen receptor(Human)
Genentech

US Patent
LigandPNGBDBM50567218(CHEMBL4877968 | US20250114338, Example 232)
Affinity DataIC50: 17nMAssay Description:Displacement of fluorescein PGC1alpha from recombinant ERalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed