BDBM50567572 CHEMBL511093::Celafolin C-1

SMILES [H][C@@]12[C@@H](OC(C)=O)[C@]3(OC1(C)C)[C@H](C)CC[C@H](OC(C)=O)[C@@]3(C)[C@@H](OC(=O)c1ccccc1)[C@@H]2OC(C)=O

InChI Key InChIKey=ZFYHVMQCJIKTLP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50567572   

TargetATP-dependent translocase ABCB1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50567572(CHEMBL511093 | Celafolin C-1)
Affinity DataIC50: 34nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KB/VCR cells assessed as potentiation of vincristine-induced antiproliferative activity by me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50567572(CHEMBL511093 | Celafolin C-1)
Affinity DataIC50: 240nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KB/VCR cells assessed as potentiation of vincristine-induced antiproliferative activity by me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed