BDBM50567573 CHEMBL4857143

SMILES [H][C@@]12[C@@H](OC(=O)\C=C\c3ccccc3)[C@]3(OC1(C)C)[C@H](C)C[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@]3(C)[C@@H](OC(=O)c1ccccc1)[C@@H]2O

InChI Key InChIKey=AYFLMIKBWXAFOA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50567573   

TargetATP-dependent translocase ABCB1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50567573(CHEMBL4857143)
Affinity DataIC50: 48nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KB/VCR cells assessed as potentiation of vincristine-induced antiproliferative activity by me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed