BDBM50567578 CHEMBL4876031

SMILES [H][C@]12C[C@H](OC(=O)c3ccccc3)[C@]3(C)[C@@H](OC(C)=O)[C@@H](C[C@@H](C)[C@@]3(OC1(C)C)[C@@H]2OC(=O)\C=C\c1ccccc1)OC(C)=O

InChI Key InChIKey=RAFMPQUGTWPMRU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50567578   

TargetATP-dependent translocase ABCB1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50567578(CHEMBL4876031)
Affinity DataIC50: 58nMAssay Description:Reversal of P-gp-mediated multidrug resistance in human KB/VCR cells assessed as potentiation of vincristine-induced antiproliferative activity by me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed