BDBM50567595 CHEMBL4850540

SMILES CC(CC(=O)N1CCC(O)(CN2C=Nc3cc(NCCN(C)C)ccc3C2O)CC1)c1ccccc1

InChI Key InChIKey=KCBJFOOQXOWGFE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50567595   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50567595(CHEMBL4850540)
Affinity DataIC50: 595nMAssay Description:Inhibition of N-terminal His-FLAG-tagged human USP7 (2 to 1102 residues) expressed in baculovirus infected Sf9 cells using Ub-AMC as substrate preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50567595(CHEMBL4850540)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of recombinant USP7 catalytic domain (unknown origin) using UbA10 as substrate incubated with substrate for 75 mins followed by compound a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed