BDBM50567882 CHEMBL4871247

SMILES Cc1ccc(s1)-c1nc(CNc2ccc(cc2)C(=O)NO)n(n1)-c1ccccc1

InChI Key InChIKey=FHHRSQAWPUUWAA-UHFFFAOYSA-N

Data  5 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50567882   

TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50567882(CHEMBL4871247)
Affinity DataKd:  7.10nMAssay Description:Binding affinity to recombinant human HDAC6 by BLI assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50567882(CHEMBL4871247)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in baculovirus infected Sf9 cells using Z-(Ac)-Lys-AMC as substrate incubated for 40 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50567882(CHEMBL4871247)
Affinity DataIC50: 224nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50567882(CHEMBL4871247)
Affinity DataIC50: 235nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50567882(CHEMBL4871247)
Affinity DataIC50: 349nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50567882(CHEMBL4871247)
Affinity DataIC50: 3.94E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Z-(Ac)-Lys-AMC as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed