BDBM50568115 CHEMBL4864190

SMILES CN1CCN(CC1)c1ccc(cc1)-n1ccc2cnc(Nc3cc(F)c(O)c(F)c3)nc12

InChI Key InChIKey=HFYKPLLUZVWVOL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50568115   

TargetRibosomal protein S6 kinase alpha-3(Human)
University of Colorado Anschutz Medical Campus

Curated by ChEMBL
LigandPNGBDBM50568115(CHEMBL4864190)
Affinity DataIC50: 35nMAssay Description:Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
University of Colorado Anschutz Medical Campus

Curated by ChEMBL
LigandPNGBDBM50568115(CHEMBL4864190)
Affinity DataEC50:  70nMAssay Description:Inhibition of RSK2 in human MOLM-13 assessed as reduction in cell viability measured after 72 hrs by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed