BDBM50568449 CHEMBL4851268

SMILES c1ccc2c(c1)C(=O)c3cc(cc(c3O2)Cl)C(=O)O

InChI Key InChIKey=XMSOQTUJOFAGGK-UHFFFAOYSA-N

Data  1 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50568449   

TargetTransthyretin(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50568449(CHEMBL4851268)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of acid-mediated aggregation of TTR V30M mutant (unknown origin) expressed in Escherichia coli pretreated for 30 mins at pH 7 followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)