BDBM50568945 CHEMBL4859351

SMILES Cn1c2nc(Nc3cccc(c3)S(C)(=O)=O)ncc2cc(-c2ccc(Cl)cc2Cl)c1=O

InChI Key InChIKey=DHLDFZDYTZKHEN-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50568945   

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University of Houston

Curated by ChEMBL

LigandBDBM50568945(CHEMBL4859351)Copy SMILESCopy InChI

Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/20/2022
Entry Details Article
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TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
University of Houston

Curated by ChEMBL

LigandBDBM50568945(CHEMBL4859351)Copy SMILESCopy InChI

Affinity DataIC50: 878nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/20/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL