BDBM50569186 CHEMBL4851627

SMILES COc1cc2CCN(Cc2cc1OC)C(=O)c1ccc(o1)-c1ccc(SC(C)C)cc1

InChI Key InChIKey=FVNGMNLMROTIHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50569186   

TargetATP-dependent translocase ABCB1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50569186(CHEMBL4851627)
Affinity DataIC50: 6.44E+4nMAssay Description:Inhibition of P-glycoprotein in human MCF7/ADR cells assessed as reversal fold by measuring reduction in doxorubicin IC50 at 5 uM incubated for 48 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed