BDBM50569199 CHEMBL4848908

SMILES Cc1c(CN2CCN(CC2)C(=O)c2cc3cccc(C(N)=O)c3o2)sc2c(nc(nc12)-c1cccc2[nH]ccc12)N1CCOCC1

InChI Key InChIKey=SDRKZXYEQNMFTG-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50569199   

TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50569199(CHEMBL4848908)Copy SMILESCopy InChI

Affinity DataIC50: 140nMAssay Description:Inhibition of PARP1 (unknown origin) using biotin-NAD+ as substrate incubated for 1 hr by ELISAMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/20/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
China Pharmaceutical University

Curated by ChEMBL

LigandBDBM50569199(CHEMBL4848908)Copy SMILESCopy InChI

Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 40 mins by ADP-glo plus luminescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/20/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL