BDBM50569537 CHEMBL4871017::US11452717, Compound TableB-2.220

SMILES Clc1ccc(cc1)S(=O)(=O)c1ccc(NC(=O)NCc2ccncc2)cc1

InChI Key InChIKey=LRFUAJAYJSNHRR-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50569537   

TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50569537(CHEMBL4871017 | US11452717, Compound TableB-2.220)
Affinity DataEC50:  126nMAssay Description:Activation of human NAMPTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50569537(CHEMBL4871017 | US11452717, Compound TableB-2.220)
Affinity DataEC50:  1.05E+3nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent