BDBM50569652 CHEMBL4874643::US11802133, Example 221

SMILES [H][C@@]12CN(CC[C@]1([H])OCC(=O)N2)C(=O)N1CC(CCc2ccc(cc2Br)C(F)(F)F)C1

InChI Key InChIKey=ZRXRIDMOUVPXIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50569652   

TargetMonoglyceride lipase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50569652(CHEMBL4874643 | US11802133, Example 221)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant MAGL (unknown origin) using 4-Nitrophenlyacetate as substrate incubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50569652(CHEMBL4874643 | US11802133, Example 221)
Affinity DataIC50: 0.700nMAssay Description:The 4-NPA assay was carried out in 384 well assay plates (black with clear bottom, non-binding surface treated, Corning Ref. 3655) in a total volume ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent