BDBM50570251 CHEMBL4856531

SMILES Cc1c(Br)cn(Cc2ccccc2F)c(=O)c1NC(=O)C1CCCCCC1

InChI Key InChIKey=CLBBWFSFMOBNAM-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50570251   

TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50570251(CHEMBL4856531)
Affinity DataEC50:  3.40nMAssay Description:Positive allosteric modulator activity at human CB2R expressed in CHO-K1 cell membrane assessed as CP55940 EC50 for [35S]GTPgammaS binding at 1 nM me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50570251(CHEMBL4856531)
Affinity DataEC50:  7nMAssay Description:Positive allosteric modulator activity at human CB2R expressed in CHO-K1 cell membrane assessed as CP55940 EC50 for [35S]GTPgammaS binding at 100 nM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50570251(CHEMBL4856531)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at human CB2R expressed in CHO-K1 cells assessed as potentiation of CP55940-stimulated beta-arrestin2 recruitm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50570251(CHEMBL4856531)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at human CB2R expressed in CHO-K1 cells assessed as potentiation of CP55940-stimulated inhibition of forskolin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed