BDBM50570431 CHEMBL4869150

SMILES Cc1cc2occ(-c3nc(c(-c4ccccc4)n3-c3ccc(Cl)c(Cl)c3)-c3ccccc3)c(=O)c2cc1Cl

InChI Key InChIKey=XNUWMPOQRIYTDT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50570431   

TargetDNA topoisomerase 2-alpha(Human)
Dr. Babasaheb Ambedkar Marathwada University

Curated by ChEMBL
LigandPNGBDBM50570431(CHEMBL4869150)
Affinity DataIC50: 3.99E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed