BDBM50570433 CHEMBL4853443

SMILES Cc1cc2occ(-c3nc(c(-c4ccccc4)n3-c3ccc(cc3)[N+]([O-])=O)-c3ccccc3)c(=O)c2cc1Cl

InChI Key InChIKey=VUUDRSRNYDEFPD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50570433   

TargetDNA topoisomerase 2-alpha(Human)
Dr. Babasaheb Ambedkar Marathwada University

Curated by ChEMBL
LigandPNGBDBM50570433(CHEMBL4853443)
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of human topoisomerase-2 alpha in human A498 cells assessed as decrease in relaxation of supercoiled DNA at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed