BDBM50570698 CHEMBL4850687

SMILES CC(=O)c1c(C)c2cnc(Nc3ccc(cn3)N3CCN(CC3)C(=O)CCl)nc2n(C2CCCC2)c1=O

InChI Key InChIKey=DHXAFRBSJGTAFK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50570698   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50570698(CHEMBL4850687)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of CDK4/Cyclin D3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50570698(CHEMBL4850687)
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK6/Cyclin D3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50570698(CHEMBL4850687)
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
LigandPNGBDBM50570698(CHEMBL4850687)
Affinity DataIC50: 3.33E+3nMAssay Description:Inhibition of CDK7/cyclin H/MAT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50570698(CHEMBL4850687)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of CDK2/cyclin A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50570698(CHEMBL4850687)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed