BDBM50570869 CHEMBL4872636

SMILES COc1cc(Cc2n[nH]c(=S)n(\N=C\c3cc4cc(C)ccc4nc3O)c2=O)cc(OC)c1OC

InChI Key InChIKey=JAGXAWLKMJLULX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570869   

TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandPNGBDBM50570869(CHEMBL4872636)
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated with enzyme for 5 mins followed by substrate addition by color...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandPNGBDBM50570869(CHEMBL4872636)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated with enzyme for 5 mins followed by substrate addition by colorimetric anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed