BDBM50570871 CHEMBL4856646

SMILES COc1ccc2nc(O)c(\C=N\n3c(=O)c(Cc4cc(OC)c(OC)c(OC)c4)n[nH]c3=S)cc2c1

InChI Key InChIKey=KOGLCIMBIYSRMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570871   

TargetProstaglandin G/H synthase 2(Human)
Zagazig University

Curated by ChEMBL
LigandPNGBDBM50570871(CHEMBL4856646)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated with enzyme for 5 mins followed by substrate addition by color...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zagazig University

Curated by ChEMBL
LigandPNGBDBM50570871(CHEMBL4856646)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated with enzyme for 5 mins followed by substrate addition by colorimetric anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed