BDBM50570886 CHEMBL4869528

SMILES C\C(=N/Nc1nc(c(CC(=O)NCCNc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)s1)-c1ccc(Cl)c(Cl)c1)C(=O)OCOC(=O)C(C)(C)C

InChI Key InChIKey=OUHYRQKOYDLKET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50570886   

TargetProtein cereblon(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570886(CHEMBL4869528)
Affinity DataIC50: 2.07E+4nMAssay Description:Binding affinity to Cereblon in human Flp293T cells transfected with BRD4(BD2)-GFP fusion protein and mCherry reporter assessed as inhibition of dBET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed