BDBM50570899 2-Mercaptobenzimidazole

SMILES Sc1nc2ccccc2[nH]1

InChI Key InChIKey=YHMYGUUIMTVXNW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50570899   

TargetPolyphenol oxidase 4(Agaricus bisporus)
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50570899(2-Mercaptobenzimidazole)
Affinity DataIC50: 150nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity using L-dopa as substrate incubated for 0.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50570899(2-Mercaptobenzimidazole)
Affinity DataIC50: 450nMAssay Description:Inhibition of mushroom tyrosinase monophenolase activity using L-tyrosine as substrate incubated for 0.5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProteasome subunit beta type-8(Human)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50570899(2-Mercaptobenzimidazole)
Affinity DataIC50: 1.14E+5nMAssay Description:Inhibition of human chymotrypsin-like beta 5i subunit of iCP using suc-LLVY-AMC as flurogenic substrate for 90 mins by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50570899(2-Mercaptobenzimidazole)
Affinity DataIC50: 5.51E+5nMAssay Description:Inhibition of recombinant human QC using H-Gln-AMC hydrobromide as fluorogenic substrate incubated for 6 hrs by fluorometric microplate reader analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed