BDBM50570900 CHEMBL4856216

SMILES Cc1ccc2[nH]c(=S)oc2c1

InChI Key InChIKey=NUMDWMDMUXZMHA-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50570900   

TargetPolyphenol oxidase 4(Agaricus bisporus)
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50570900(CHEMBL4856216)
Affinity DataIC50: 80nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 30 mins by absorbance based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50570900(CHEMBL4856216)
Affinity DataKi:  98nMAssay Description:Binding affinity to mushroom tyrosinase using L-DOPA as substrate assessed as inhibition constant by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50570900(CHEMBL4856216)
Affinity DataIC50: 130nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate incubated for 30 mins by absorbance based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProteasome subunit beta type-8(Human)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50570900(CHEMBL4856216)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human chymotrypsin-like beta 5i subunit of iCP using suc-LLVY-AMC as flurogenic substrate for 90 mins by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50570900(CHEMBL4856216)
Affinity DataKd:  1.00E+6nMAssay Description:Binding affinity to Keap1 kelch domain (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed