BDBM50570938 Benzooxazole-2-thiol::Benzoxazole-2-Thiol::CHEMBL113414

SMILES Sc1nc2ccccc2o1

InChI Key InChIKey=FLFWJIBUZQARMD-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50570938   

TargetProteasome subunit beta type-8(Human)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50570938(CHEMBL113414 | Benzooxazole-2-thiol | Benzoxazole-...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human chymotrypsin-like beta 5i subunit of iCP using suc-LLVY-AMC as flurogenic substrate for 90 mins by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50570938(CHEMBL113414 | Benzooxazole-2-thiol | Benzoxazole-...)
Affinity DataIC50: 80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50570938(CHEMBL113414 | Benzooxazole-2-thiol | Benzoxazole-...)
Affinity DataIC50: 240nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50570938(CHEMBL113414 | Benzooxazole-2-thiol | Benzoxazole-...)
Affinity DataKi:  58nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed