BDBM50571001 CHEMBL4872231

SMILES COc1ccc(cc1)C1=N\C(=C\c2ccc(O)cc2)C(=O)N1c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=NYAREIXEICMJFJ-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50571001   

TargetCarbonic anhydrase 2(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50571001(CHEMBL4872231)
Affinity DataKi:  0.830nMAssay Description:Inhibition of human CA2 by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50571001(CHEMBL4872231)
Affinity DataKi:  6.90nMAssay Description:Inhibition of human CA4 by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50571001(CHEMBL4872231)
Affinity DataKi:  12nMAssay Description:Inhibition of human CA9 by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50571001(CHEMBL4872231)
Affinity DataKi:  95nMAssay Description:Inhibition of human CA1 by stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50571001(CHEMBL4872231)
Affinity DataIC50: 140nMAssay Description:Inhibition of p38alphaMAPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed