BDBM50571008 CHEMBL4873958

SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc(NC(=O)CN(C)C)c3)cc2)c(=O)n(-c2ccc(F)cc2)c1=O

InChI Key InChIKey=NCYONVSVKQVALR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50571008   

TargetTyrosine-protein kinase receptor UFO(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571008(CHEMBL4873958)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human GST-tagged Axl incubated for 1 hr by ADP-glo based luminometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571008(CHEMBL4873958)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human GST-tagged Mer using biotinylated peptide as substrate incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571008(CHEMBL4873958)
Affinity DataIC50: 68nMAssay Description:Inhibition of recombinant human Mer expressed in mouse BaF3 cells assessed as reduction in cell viability incubated for 2 days by cell titer glo assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571008(CHEMBL4873958)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human Axl expressed in mouse BaF3 cells assessed as reduction in cell viability incubated for 2 days by cell titer glo assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed