BDBM50571013 CHEMBL4867578

SMILES CN1CCC(CC(=O)Nc2cc(Oc3ccc(NC(=O)c4cc5C(=O)CCCc5n(-c5ccccc5)c4=O)cc3)ccn2)CC1

InChI Key InChIKey=URJHRMXSWREGLT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50571013   

TargetTyrosine-protein kinase receptor UFO(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571013(CHEMBL4867578)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant human GST-tagged Axl incubated for 1 hr by ADP-glo based luminometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571013(CHEMBL4867578)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human GST-tagged Mer using biotinylated peptide as substrate incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed