BDBM50571027 CHEMBL4873739

SMILES CN1CCN(CC1)C1CCN(CC1)C(=O)Nc1cc(Oc2ccc(NC(=O)c3cn(C4CC4)c(=O)n(-c4ccc(F)cc4)c3=O)cc2)ncn1

InChI Key InChIKey=BQOPPXMDAUTYSM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50571027   

TargetTyrosine-protein kinase receptor UFO(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571027(CHEMBL4873739)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of recombinant human GST-tagged Axl incubated for 1 hr by ADP-glo based luminometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571027(CHEMBL4873739)
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant human Axl expressed in mouse BaF3 cells assessed as reduction in cell viability incubated for 2 days by cell titer glo assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571027(CHEMBL4873739)
Affinity DataIC50: 234nMAssay Description:Inhibition of recombinant human GST-tagged Mer using biotinylated peptide as substrate incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50571027(CHEMBL4873739)
Affinity DataIC50: 304nMAssay Description:Inhibition of recombinant human Mer expressed in mouse BaF3 cells assessed as reduction in cell viability incubated for 2 days by cell titer glo assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed