BDBM50571721 CHEMBL4874046

SMILES CNC(=O)c1ccc(Nc2ncc(c(Nc3ccccc3OC)n2)C(F)(F)F)cc1

InChI Key InChIKey=MZKCTWNUCVKGCB-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50571721   

TargetFocal adhesion kinase 1(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571721(CHEMBL4874046)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of FAK (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571721(CHEMBL4874046)
Affinity DataIC50: 292nMAssay Description:Inhibition of VEGFR-2 (unknown origin) incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571721(CHEMBL4874046)
Affinity DataIC50: 24nMAssay Description:Inhibition of Pyk2 (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571721(CHEMBL4874046)
Affinity DataIC50: 18nMAssay Description:Inhibition of TRKA (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571721(CHEMBL4874046)
Affinity DataIC50: 39nMAssay Description:Inhibition of TRKB (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetNT-3 growth factor receptor(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571721(CHEMBL4874046)
Affinity DataIC50: 30nMAssay Description:Inhibition of TRKC (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571721(CHEMBL4874046)
Affinity DataIC50: 18nMAssay Description:Inhibition of JAK2 (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571721(CHEMBL4874046)
Affinity DataIC50: 20nMAssay Description:Inhibition of JAK3 (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50571721(CHEMBL4874046)
Affinity DataIC50: 22nMAssay Description:Inhibition of TYK2 (unknown origin) measured after 40 mins by HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed