BDBM50572105 CHEMBL4872031

SMILES [H][C@]12CCCN(CCOc3ccn4c(cnc4c3)-c3cc(NCc4ccc(cc4)-c4cnn(C)c4)ncn3)[C@@]1([H])CCO2

InChI Key InChIKey=LPVPQEXAFSGDOJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50572105   

TargetMast/stem cell growth factor receptor Kit(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50572105(CHEMBL4872031)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant C-KIT V654A mutant (544 to end residues) using GGMEDIYEFMGGKKK as substrate measured after 40 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed