BDBM50572892 CHEMBL4873692

SMILES Cn1ccc2c(ccnc12)-c1ccc(C(O)=O)c(c1)C1CCCC1

InChI Key InChIKey=QVKRXPQUPKYNFR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50572892   

TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50572892(CHEMBL4873692)
Affinity DataIC50: 56nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50572892(CHEMBL4873692)
Affinity DataIC50: 470nMAssay Description:Inhibition of NanoLuc-fused CAMKK2 (unknown origin) expressed in HEK293 cells after 24 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 1(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50572892(CHEMBL4873692)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of human CAMKK1 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed