BDBM50573129 CHEMBL4872116

SMILES COc1cc(ccc1-c1nnc(o1)N(C)Cc1ccc2nccn2c1)-c1c(C)nn(C)c1C

InChI Key InChIKey=POLOQBZTXAWWJT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50573129   

TargetTyrosine-protein kinase Mer(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573129(CHEMBL4872116)
Affinity DataIC50: 16nMAssay Description:Inhibition of MER (unknown origin) by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573129(CHEMBL4872116)
Affinity DataIC50: 501nMAssay Description:Inhibition of FLAG-tagged MER (unknown origin) transfected in Cos-7cells assessed as phosphorylation level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573129(CHEMBL4872116)
Affinity DataIC50: 794nMAssay Description:Inhibition of AXL (unknown origin) by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573129(CHEMBL4872116)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of FLAG-tagged AXL (unknown origin) transfected in Cos-7 cells assessed as phosphorylation level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573129(CHEMBL4872116)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of FLAG-tagged FLT3 (unknown origin) transfected in Cos-7 cells assessed as phosphorylation level incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50573129(CHEMBL4872116)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of FLT3 (unknown origin) by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed