BDBM50573472 CHEMBL4872958

SMILES Cn1ncc2cc(ccc12)-c1cnc2[nH]ncc2c1N1CCC2(CCNC2=O)CC1

InChI Key InChIKey=CEWMHXPZWYBDGS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50573472   

TargetCyclin-C(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50573472(CHEMBL4872958)
Affinity DataIC50: 178nMAssay Description:Inhibition of tracer 236 binding to recombinant human His-tagged full length CDK8/Cyclin C expressed in baculovirus expression system by Lanthascreen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50573472(CHEMBL4872958)
Affinity DataIC50: 214nMAssay Description:Inhibition of tracer 236 binding to recombinant human GST/His-tagged CDK11 (1 to 502 residues)/Cyclin C( 1 to 283 residues) expressed in insect cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed