BDBM50573707 CHEMBL4866610

SMILES [H][C@@]12CCN1C(=O)CCCCCOC[C@H](NC2=O)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1

InChI Key InChIKey=SMYVVJLREYNLQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50573707   

TargetProteasome subunit beta type-9(Human)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50573707(CHEMBL4866610)
Affinity DataIC50: 262nMAssay Description:Inhibition of human LMP2 using Ac-PAL-AMC as substrate preincubated for 30 mins followed by substrate addition and measured after 90 min by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProteasome subunit beta type-9(Human)
Florida International University

Curated by ChEMBL
LigandPNGBDBM50573707(CHEMBL4866610)
Affinity DataIC50: 262nMAssay Description:Inhibition of human 20S proteasome LMP2 using Ac-PAL-AMC as fluorogenic substrate measured every minute for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50573707(CHEMBL4866610)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 20S proteasome LMP7 using Ac-ANW-AMC as fluorogenic substrate measured every minute for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed