BDBM50573716 CHEMBL4874168

SMILES CCOc1cc2CCN3CC(CC(C)C)C(O)CC3c2cc1OC

InChI Key InChIKey=GMIKCMWFQLESAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50573716   

TargetSynaptic vesicular amine transporter(Rat)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50573716(CHEMBL4874168)
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetSynaptic vesicular amine transporter(Rat)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50573716(CHEMBL4874168)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptosome incubated for 10 mins followed by [3H]DA addition and measured after 20 mins by TopC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed