BDBM50574076 CHEMBL4855850

SMILES FS(=O)(=O)c1ccc(CN2CCN(CC2)c2nc(Nc3cc([nH]n3)C3CC3)cc(n2)C(=O)NCC#C)cc1

InChI Key InChIKey=ZBSPMOBILDLOCV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50574076   

TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50574076(CHEMBL4855850)
Affinity DataIC50: 244nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using fluoresceine-labelled poly-GT peptide as substrate incubated for 1 hr by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50574076(CHEMBL4855850)
Affinity DataIC50: 6nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using fluoresceine-labelled poly-GT peptide as substrate preincubated with enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed