BDBM50574079 CHEMBL4846276

SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2cccc(c2)C(=O)Oc2ccc(F)cc2)n1)N1CCN(CC1)C(C)=O

InChI Key InChIKey=NGKWAEIDLVDZDY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50574079   

TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50574079(CHEMBL4846276)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) using fluoresceine-labelled poly-GT peptide as substrate incubated for 1 hr by TR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed